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NEW YORK (CNNMoney) -- U.S. stocks were poised to open lower Wednesday, as investors trade cautiously ahead of big events at home and abroad later this week.
U.S. stock futures slid into the red as investors wait to take cues from jobs numbers due out Friday and to see whether the European Central Bank acts to protect the euro when the central bank meets Thursday morning.
Following more disappointing manufacturing numbers Tuesday, investors are looking at all economic numbers with an eye to how they could influence the Federal Reserve's decision to announce more quantitative easing at its Sept. 12-13 policy meeting.
Related: Election won't stop the Fed
U.S. stocks closed in mixed territory Tuesday as the reports indicating manufacturing and construction spending slumps dragged on markets.
World Markets: European stocks were mixed in morning trading. Britain's FTSE 100 slid 0.1% and France's CAC 40 fell 0.5%, while the DAX in Germany ticked up 0.1%.
Asian markets closed lower Wednesday. The Shanghai Composite shed 0.3%, the Hang Seng in Hong Kong dropped 1.5%, and Japan's Nikkei lost 1.1%.
Companies: Dollar General (DG, Fortune 500) will report its second-quarter financial results before the opening bell. The discount retailer is expected to report earnings of 64 cents a share, on $4 billion in revenue.
Shares of FedEx (FDX, Fortune 500) continued to fall in premarket trading, after the company cut its outlook for the quarter, citing weakness in the global economy. United Parcel Service Inc (UPS, Fortune 500) was also lower on the news.
After hitting another all-time low on Tuesday, Facebook (FB) gained nearly 2% in after-hours trading when CEO Mark Zuckerberg announced that he will not sell his shares for a year.
Related: Facebook hits new low
Apple (AAPL, Fortune 500) shares slid slightly in premarket trading Wednesday, after ending the prior session higher on an announcement of an event for Sept. 12, at which Apple is widely expected to introduce a new iPhone.
Economy: Traders will watch for the government's revised reading on second-quarter productivity, which comes out at 8:30 a.m. ET. The report is expected to show that business-sector output was slightly stronger than previous estimates.
Currencies and commodities: The dollar rose against the euro, the British pound and the Japanese yen.
Oil for October delivery fell 25 cents to $95.05 a barrel.
Gold futures for December delivery lost $3.40 to $1,694.80 an ounce.
Bonds: The price on the benchmark 10-year U.S. Treasury fell, pushing the yield up to 1.58% from 1.56% late Tuesday.
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